Screening for Monogenic Lupus in Patients With Childhood Onset Systemic Lupus Erythematosus
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
The purpose of this study is to unravel the proportion of monogenic lupus in children onset Systemic lupus erythematosus (SLE), and to find out the diagnostic strategy for early detection of monogenic lupus.
Eligibility
Participation Requirements
Sex: All
Maximum Age: 18
Healthy Volunteers: f
View:
⁃ Subjects who meet the following criteria will be allowed to participate in the study:
• onset age: birth to 18 years;
• meet the diagnostic criteria of SLE according to ACR(1997), or SLICC(2012), or EULAR/ACR (2019);
• obtain parental consent.
Locations
Other Locations
China
Children's Hospital of Fudan University
RECRUITING
Shanghai
Contact Information
Primary
YINV GONG
gongyinv@163.com
+8615921439339
Backup
Li SUN, PI
lillysun@263.net
86-21-64932829
Time Frame
Start Date: 2020-11-25
Estimated Completion Date: 2025-09-30
Participants
Target number of participants: 200
Treatments
Patients with childhood onset SLE
Participants in this group were derived from patients diagnosed with SLE at an age of less than 18 years old, and these patients were hospitalized in our center. Peripheral blood was collected from the patient and their biological parents for gene analysis to obtain the overall incidence of monogenic lupus in the cohort.
Related Therapeutic Areas
Sponsors
Leads: Children's Hospital of Fudan University